Ending HIV as a public health threat by sustaining and accelerating a comprehensive HIV and TB response in India under the President's Emergency Plan for AIDS Relief (PEPFAR) | CDC RFA JG 25 0103

Opportunity Information: Apply for CDC RFA JG 25 0103

The Centers for Disease Control and Prevention (CDC), through PEPFAR, is offering a discretionary cooperative agreement opportunity focused on helping India move closer to ending HIV as a public health threat by sustaining and accelerating a comprehensive HIV and tuberculosis (TB) response. The program is designed to support Indias National AIDS Control Program (NACP) as it works to maintain HIV epidemic control and improve outcomes in priority geographic areas, such as Andhra Pradesh and other locations as applicable. The emphasis is on strengthening performance across the full prevention-to-treatment continuum, with a clear focus on improving viral load suppression (VLS), which is one of the most important indicators of effective HIV treatment and reduced onward transmission.

This opportunity aligns with NACP Phase V and asks applicants to build on innovative, evidence-based, and person-centered strategies. In practical terms, this means activities should be grounded in proven public health approaches while also tailoring services to the needs and realities of people and communities affected by HIV and TB. The scope spans both diseases, reflecting the close relationship between HIV and TB in terms of risk, diagnosis, and health outcomes, and it encourages integrated approaches that can improve patient pathways and reduce missed opportunities for prevention and care.

Key program priorities include strengthening HIV and TB prevention, improving HIV and TB case-finding, and expanding or refining tools that improve TB case identification. The funding also targets the steps that determine whether people actually benefit from diagnosis and treatment services: stronger linkage to the care continuum, better treatment retention over time, and higher levels of viral load suppression among people receiving antiretroviral therapy. Taken together, these areas reflect the biggest leverage points for improving population-level outcomes: finding people who are not yet diagnosed, connecting them quickly to appropriate care, and supporting them to stay on treatment long enough to achieve and maintain viral suppression.

A central expectation is that applicants will present an innovative and credible plan to collaborate closely with government partners and the wider ecosystem involved in the HIV and TB response. This includes working with district, state, and national teams, engaging communities, coordinating with private sector organizations, and partnering with other stakeholders to identify and close program gaps. The cooperative agreement structure also implies substantial involvement from CDC beyond simple funding, typically through ongoing technical guidance, joint planning, and performance monitoring, so proposals should be prepared for regular collaboration, reporting, and adaptive management based on results.

The notice highlights several examples of the kinds of technical assistance and support activities that may be funded. These include efforts to close testing, treatment, and equity gaps, which can involve addressing disparities across populations, geographies, or service settings and improving access for underserved groups. It also includes reinforcing collaborations that complement NACP, meaning funded work should fit into and strengthen national and subnational plans rather than operate as a stand-alone parallel program. Another major focus is improving data use for impact, which points to strengthening surveillance, program monitoring, data quality, and the translation of data into decisions that improve coverage and outcomes. Finally, applicants are encouraged to expand the ability to respond to emerging public health threats, signaling interest in capabilities that improve resilience and readiness, such as adaptable service delivery models, stronger public health coordination, and systems that can pivot during disruptions.

From an administrative standpoint, this is CDC Funding Opportunity Number CDC RFA JG 25 0103 under CFDA 93.067. The anticipated total funding for Fiscal Year 1 is approximately USD 4,000,000, subject to availability of funds. The listing notes that the award ceiling for Year 1 is listed as 0 (none), which generally indicates that an upper cap is not specified in the notice even though an overall funding amount is anticipated. CDC expects to make two awards. The original closing date for applications is 2025-02-24, and the opportunity was created on 2024-12-06. Eligibility is broad and includes various levels of government, public and private institutions of higher education, nonprofit organizations (including 501(c)(3) and non-501(c)(3) entities), for-profit organizations (including small businesses), tribal governments and organizations, public housing authorities, and unrestricted applicants, which means a wide range of implementing partners may apply if they can demonstrate the technical capacity and partnerships needed to support NACP priorities.

• The Centers for Disease Control-GHC in the health sector is offering a public funding opportunity titled "Ending HIV as a public health threat by sustaining and accelerating a comprehensive HIV and TB response in India under the President's Emergency Plan for AIDS Relief (PEPFAR)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
• This funding opportunity was created on 2024-12-06.
• Applicants must submit their applications by 2025-02-24. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• The number of recipients for this funding is limited to 2 candidate(s).
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Unrestricted.

Apply for CDC RFA JG 25 0103

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