Opportunity Information: Apply for RFA OH 23 001
The Exploratory/Developmental Grants Related to the World Trade Center Health Program (R21) opportunity (RFA OH 23 001) is a discretionary federal grant program administered by the Department of Health and Human Services through the CDC, with support from NIOSH. It is designed to fund early-stage, innovative research that tests new or nontraditional intervention ideas aimed at improving health outcomes for people connected to the World Trade Center Health Program. The target population includes enrolled WTC responders and certified-eligible WTC survivors who receive medical monitoring and or treatment under Subtitle B of the James Zadroga 9/11 Health and Compensation Act of 2010, as later amended. The central theme is intervention research that can reduce risk factors tied to the most common causes of illness and death in this population, with an emphasis on practical approaches that can be sustained over time.
A key feature of this R21 mechanism is its exploratory and developmental nature. Applicants are expected to propose concepts that may have minimal or even no preliminary data, which signals that NIOSH is intentionally encouraging high-potential, earlier-stage intervention ideas rather than requiring mature programs with extensive prior results. Projects should focus on modifiable health behaviors and lifestyle factors that meaningfully shape quality of life and longer-term clinical trajectories, including disease progression and recurrence, survival, adverse events, and other measurable health-related outcomes. Examples of the priority areas described in the announcement include nutrition and diet, sleep hygiene, stress management and positive psychology approaches, physical activity, social connectedness, and preventing or reducing substance misuse. NIOSH also indicates it is seeking a balanced portfolio, meaning it wants a mix of projects and intervention types rather than a narrow concentration in only one topic area.
The opportunity is open to a wide range of applicants across government, education, nonprofit, and private sectors. Eligible organizations include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments as well as other tribal organizations; public housing authorities and Indian housing authorities; nonprofits with or without 501(c)(3) status (as long as they are not institutions of higher education in those categories); for-profit organizations other than small businesses; and small businesses. In practice, this broad eligibility is meant to attract diverse research teams and settings that can design and test interventions relevant to WTC Health Program members, whether delivered through clinical programs, community partnerships, digital tools, or other implementation channels consistent with the goals of the program.
From a funding and timeline standpoint, the grant uses the R21 funding instrument and is listed under CFDA 93.262. The award ceiling is $500,000, and the agency anticipated making about 8 awards under this announcement. The application due date listed in the source information was December 6, 2022, with electronic submissions due by 5:00 pm Eastern Time on the deadline date. Overall, the announcement signals interest in creative, feasible intervention studies that can be piloted and evaluated in ways that generate early evidence, inform larger follow-on studies, and ultimately improve health and well-being among WTC responders and survivors receiving services through the WTC Health Program.Apply for RFA OH 23 001
- The Department of Health and Human Services, Centers for Disease Control and Prevention - ERA in the health sector is offering a public funding opportunity titled "Exploratory/Developmental Grants Related to the World Trade Center Health Program (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.262.
- This funding opportunity was created on Aug 29, 2022.
- Applicants must submit their applications by Dec 06, 2022 Electronically submitted applications must be submitted no later than 500 pm Eastern Time on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $500,000.00 in funding.
- The number of recipients for this funding is limited to 8 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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