Opportunity Information: Apply for PA 24 177
The Mentored Research Scientist Development Award (K01) is an NIH career development grant designed to help promising researchers move toward full research independence. It provides substantial protected time and financial support for an intensive, closely supervised career development period lasting three to five years. The award is meant for investigators working in biomedical, behavioral, or clinical science, and it emphasizes structured mentoring, targeted training, and a clear plan that helps the candidate build the skills, publication record, and preliminary data needed to compete successfully for independent research funding later on.
A key theme of this particular parent K01 opportunity is that it is intended for research career development that includes independent basic experimental studies with humans. In practice, that means applicants should expect the research component to involve prospective assignment of human participants to conditions or interventions (or other forms of experimental manipulation) in order to understand fundamental biological, behavioral, or related mechanisms. Because this is a mentored mechanism, the proposal is generally expected to show a strong, hands-on mentoring team and an environment that can realistically support the candidate in conducting rigorous human studies while also completing career development activities such as advanced coursework, workshops, technical training, and professional development.
While all participating NIH Institutes and Centers use the K01 to cultivate research independence, the announcement highlights that different NIH components may apply the mechanism in slightly different ways. Some Institutes and Centers use K01 awards to help investigators transition into a new scientific field, giving them time and structured mentoring to retrain and build credibility in a different area. Others may prioritize applicants who have experienced a significant career interruption due to illness or major family responsibilities and need a supported pathway to reestablish research momentum. In addition, some NIH components use the K01 to develop expertise in particular scientific disciplines or priority research areas, so applicants typically need to pay attention to Institute- and Center-specific interests when deciding where the application best fits.
Eligibility is broad and includes many types of U.S.-based organizations. Eligible applicants listed for this opportunity include state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations that are not federally recognized; public housing authorities and Indian housing authorities; nonprofits with or without 501(c)(3) status (as long as they are not institutions of higher education, which are listed separately); for-profit organizations other than small businesses; and small businesses. The announcement also explicitly calls out additional eligible applicant categories such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations, eligible agencies of the federal government, regional organizations, and U.S. territories or possessions.
At the same time, there are clear restrictions related to foreign involvement. Non-domestic (non-U.S.) entities (foreign organizations) are not eligible to apply as the applicant organization. Non-domestic components of U.S. organizations are also not eligible to apply. However, “foreign components” are allowed as defined in the NIH Grants Policy Statement, meaning a U.S. applicant organization can include certain well-justified international elements within the project when permitted by NIH policy, even though the applicant institution itself must be domestic.
Administratively, this is an NIH discretionary grant opportunity (Funding Instrument: Grant) under the parent K01 announcement titled “Mentored Research Scientist Development Award (Parent K01 Independent Basic Experimental Studies with Humans Required),” Funding Opportunity Number PA-24-177. It is associated with multiple CFDA numbers (including 93.113, 93.121, 93.173, 93.213, 93.242, 93.273, 93.279, 93.310, 93.313, 93.361, 93.398, 93.865, and 93.866), reflecting participation across different NIH Institutes and Centers. The opportunity was created on April 24, 2024, and the listed original closing date is May 7, 2027. The announcement does not specify an award ceiling or expected number of awards in the provided data, which typically means those details may vary by NIH Institute/Center, budget requests, and available appropriations, and applicants should consult the full NIH posting and Institute-specific guidance when planning a budget and submission strategy.Apply for PA 24 177
- The National Institutes of Health in the education, environment, health, income security and social services sector is offering a public funding opportunity titled "Mentored Research Scientist Development Award (Parent K01 Independent Basic Experimental Studies with Humans Required)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.173, 93.213, 93.242, 93.273, 93.279, 93.310, 93.313, 93.361, 93.398, 93.865, 93.866.
- This funding opportunity was created on 2024-04-24.
- Applicants must submit their applications by 2027-05-07.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Applicants also applied for:
Applicants who have applied for this opportunity (PA 24 177) also looked into and applied for these:
| Funding Opportunity |
|---|
| NIH Pathway to Independence Award (Parent K99/R00 Independent Basic Experimental Studies with Humans Required) Apply for PA 24 195 Funding Number: PA 24 195 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Small Business Transition Grant for New Entrepreneurs (R41/R42 Clinical Trial Not Allowed) Apply for PAR 24 133 Funding Number: PAR 24 133 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| PHS 2024-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required) Apply for PA 24 248 Funding Number: PA 24 248 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Postdoctoral Career Transition Award to Promote Diversity (K99/R00 - Independent Basic Experimental Studies with Humans Required (BESH)) Apply for PAR 24 227 Funding Number: PAR 24 227 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Human Brain Single-cell Genomics Explorer (U24 - Clinical Trial Not Allowed) Apply for RFA NS 24 038 Funding Number: RFA NS 24 038 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $1,000,000 |
| Environmental Health Disparities Centers (P50) Clinical Trial Optional Apply for RFA MD 24 010 Funding Number: RFA MD 24 010 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed) Apply for PAR 25 233 Funding Number: PAR 25 233 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Dissemination and Implementation Research in Health (R21 Clinical Trial Optional) Apply for PAR 25 143 Funding Number: PAR 25 143 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32) Apply for PA 25 168 Funding Number: PA 25 168 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed) Apply for PAR 25 298 Funding Number: PAR 25 298 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $375,000 |
| NIH Small Research Grant Program (Parent R03 Clinical Trial Not Allowed) Apply for PA 25 302 Funding Number: PA 25 302 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $50,000 |
| NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Not Allowed) Apply for PA 25 304 Funding Number: PA 25 304 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required) Apply for PA 25 306 Funding Number: PA 25 306 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional) Apply for PAR 25 371 Funding Number: PAR 25 371 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional) Apply for PAR 25 369 Funding Number: PAR 25 369 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional) Apply for PAR 25 370 Funding Number: PAR 25 370 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $50,000 |
| Intervention Research to Improve Native American Health (R34 Clinical Trial Optional) Apply for PAR 25 378 Funding Number: PAR 25 378 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Basic Experimental Studies with Human Required) Apply for PAR 25 323 Funding Number: PAR 25 323 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
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