Opportunity Information: Apply for PAR 22 112
The Urgent Award: COVID-19 Mental Health Research (R01 Clinical Trial Required) (Funding Opportunity Number PAR 22-112) is a discretionary grant program from the National Institutes of Health (NIH), specifically aligned with the National Institute of Mental Health (NIMH), to support time-sensitive research addressing mental health needs and consequences linked to the COVID-19 pandemic. The activity sits in the health funding category (CFDA 93.242) and uses the R01 mechanism, meaning it is intended for substantial, hypothesis-driven projects that can produce rigorous, generalizable findings. A key feature of this particular opportunity is that it is “Clinical Trial Required,” which signals that the proposed work must include a clinical trial component and is expected to test an intervention, service approach, or other trial-appropriate strategy rather than only observational or descriptive research.
The overall purpose of the opportunity is to accelerate mental health research that responds to urgent pandemic-related issues. In practical terms, this type of NIMH urgent award is designed for projects that cannot wait for a normal research timeline because the public health context creates immediate and evolving needs. While the provided source text does not list specific scientific priorities, the title and NIMH framing strongly indicate interest in studies that evaluate clinically meaningful outcomes related to mental health during or in the aftermath of COVID-19, such as prevention or treatment approaches, service delivery models, and other intervention strategies that can be tested through a clinical trial and inform near-term decision-making in real-world settings.
The funding instrument is a grant, with an award ceiling listed at $750,000. The source data does not specify the total number of expected awards, which often means the number may depend on application volume, merit, and available appropriations. The original closing date for submissions was December 23, 2022, and the opportunity record was created on January 31, 2022, which places it squarely in the period when federal agencies were still actively standing up targeted COVID-19 research efforts.
Eligibility is broad and spans many types of U.S. and non-U.S. organizations. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; and public housing authorities/Indian housing authorities. Academic applicants can include public and state-controlled institutions of higher education as well as private institutions of higher education. Tribal eligibility includes federally recognized Native American tribal governments and Native American tribal organizations that are not federally recognized governments, and the announcement also highlights Indian/Native American Tribal Governments (Other than Federally Recognized) as an additional eligible applicant category. The program is open to nonprofits both with and without 501(c)(3) status (as long as they are not institutions of higher education under that classification), and it also allows for-profit organizations (other than small businesses) and small businesses. The “Others” category is included as well, which typically serves as a catch-all for eligible entities not neatly captured in the standard list.
In addition to the standard eligibility list, the opportunity explicitly calls out several institution types and community-oriented organizations as “Other Eligible Applicants.” These include Alaska Native and Native Hawaiian Serving Institutions; Asian American, Native American, and Pacific Islander Serving Institutions (AANAPISIs); Hispanic-serving institutions; Historically Black Colleges and Universities (HBCUs); and Tribally Controlled Colleges and Universities (TCCUs). It also includes faith-based or community-based organizations, eligible agencies of the federal government, regional organizations, non-domestic (non-U.S.) entities (foreign organizations), and U.S. territories or possessions. Taken together, this emphasis reflects an intent to support research that can be carried out in diverse settings and with partners that are closely connected to populations disproportionately affected by the pandemic and by behavioral health access gaps.
Because it is an R01 with a clinical trial requirement, applicants would generally be expected to propose a well-justified trial design, clearly defined primary and secondary outcomes, an appropriate recruitment and retention plan, and safeguards for participants. Projects that align with an “urgent award” framing typically need to make a strong case that the work is both feasible on an accelerated timeline and likely to yield actionable findings relevant to COVID-19-related mental health challenges.Apply for PAR 22 112
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Urgent Award: COVID-19 Mental Health Research (R01 Clinical Trial Required)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242.
- This funding opportunity was created on 2022-01-31.
- Applicants must submit their applications by 2022-12-23. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $750,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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FAQs: The Urgent Award: COVID-19 Mental Health Research (R01 Clinical Trial Required) - PAR 22-112
What is this grant opportunity?
This opportunity is titled The Urgent Award: COVID-19 Mental Health Research (R01 Clinical Trial Required) with Funding Opportunity Number PAR 22-112. It is a discretionary grant program from the National Institutes of Health (NIH), aligned with the National Institute of Mental Health (NIMH), and it supports time-sensitive research addressing mental health needs and consequences linked to the COVID-19 pandemic.
Which NIH institute is this aligned with?
The opportunity is specifically aligned with the National Institute of Mental Health (NIMH).
What is the main goal of this urgent award?
The purpose is to accelerate mental health research that responds to urgent, pandemic-related issues. The intent is to support projects where the public health context creates immediate and evolving needs, meaning the work cannot wait for a normal research timeline.
What funding mechanism does this opportunity use?
This opportunity uses the R01 mechanism, which is intended for substantial, hypothesis-driven projects capable of producing rigorous, generalizable findings.
Does the project have to include a clinical trial?
Yes. A defining feature of this opportunity is that it is "Clinical Trial Required". The proposed work must include a clinical trial component and is expected to test an intervention, service approach, or other trial-appropriate strategy rather than only observational or descriptive research.
Are observational or descriptive studies eligible under this announcement?
Based on the description provided, the opportunity emphasizes that a clinical trial is required and that projects are expected to test an intervention or service approach. Work that is only observational or descriptive would not match that clinical trial requirement as described.
What kinds of research topics are implied by the description?
While specific scientific priorities are not listed in the provided information, the title and NIMH framing indicate interest in studies evaluating clinically meaningful mental health outcomes during or after COVID-19. Examples implied include prevention or treatment approaches, service delivery models, and other intervention strategies that can be tested through a clinical trial and inform near-term decision-making in real-world settings.
What is the funding category and CFDA number?
The activity sits in the health funding category and is associated with CFDA 93.242.
What type of funding instrument is used?
The funding instrument is a grant.
What is the maximum award amount (award ceiling)?
The award ceiling listed for this opportunity is $750,000.
How many awards will NIH make?
The provided information does not specify the number of expected awards. When this is not listed, it often means awards may depend on application volume, scientific merit, and available appropriations.
When was the opportunity posted and when was it due?
The record was created on January 31, 2022, and the original closing date for submissions was December 23, 2022.
Who is eligible to apply?
Eligibility is broad and includes many U.S. and non-U.S. organizations. Eligible applicants listed include governmental entities, academic institutions, tribal entities, nonprofits, for-profit organizations (including small businesses), and other eligible entity types described in the announcement.
Are state, local, or special district governments eligible?
Yes. Eligible applicants include state, county, and city or township governments, as well as special district governments.
Are independent school districts eligible?
Yes. Independent school districts are listed as eligible applicants.
Are public housing authorities eligible?
Yes. Public housing authorities/Indian housing authorities are included in the eligibility list.
Are colleges and universities eligible?
Yes. Eligible academic applicants include public and state-controlled institutions of higher education and private institutions of higher education.
Are tribal governments and tribal organizations eligible?
Yes. Eligibility includes federally recognized Native American tribal governments and Native American tribal organizations (other than federally recognized tribal governments). The information also highlights Indian/Native American Tribal Governments (Other than Federally Recognized) as an eligible category.
Are nonprofits eligible? What about organizations without 501(c)(3) status?
Yes. The program is open to nonprofits with and without 501(c)(3) status (as long as they are not institutions of higher education under that classification), based on the eligibility description provided.
Are for-profit organizations eligible?
Yes. For-profit organizations (other than small businesses) are listed as eligible, and small businesses are also listed as eligible.
Are foreign (non-U.S.) organizations eligible to apply?
Yes. The opportunity includes non-domestic (non-U.S.) entities (foreign organizations) among the "Other Eligible Applicants."
Are U.S. territories or possessions eligible?
Yes. U.S. territories or possessions are included among the "Other Eligible Applicants."
Are faith-based or community-based organizations eligible?
Yes. The opportunity specifically includes faith-based or community-based organizations as "Other Eligible Applicants."
Are minority-serving institutions specifically mentioned as eligible?
Yes. The opportunity explicitly calls out several institution types as "Other Eligible Applicants," including Alaska Native and Native Hawaiian Serving Institutions, Asian American, Native American, and Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs).
Are federal agencies eligible to apply?
Yes. The opportunity includes eligible agencies of the federal government among the "Other Eligible Applicants."
Are regional organizations eligible?
Yes. Regional organizations are listed among the "Other Eligible Applicants."
What does the "Others" eligibility category mean?
The description notes an "Others" category, which typically serves as a catch-all for eligible entities not neatly captured in the standard list. The provided information does not define it further.
What makes a project a good fit for an "urgent award" framing?
Projects typically need to make a strong case that the work is time-sensitive, feasible on an accelerated timeline, and likely to yield actionable findings relevant to COVID-19-related mental health challenges.
What trial elements are applicants generally expected to address for an R01 clinical trial?
Because this is an R01 with a clinical trial requirement, applicants would generally be expected to propose a well-justified trial design, clearly defined primary and secondary outcomes, an appropriate recruitment and retention plan, and safeguards for participants, consistent with what is described for this opportunity.
Is this opportunity specifically tied to COVID-19?
Yes. The opportunity is explicitly focused on mental health needs and consequences linked to the COVID-19 pandemic, including during the pandemic and in its aftermath.
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Applicants also applied for:
Applicants who have applied for this opportunity (PAR 22 112) also looked into and applied for these:
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| Health Equity and the Cost of Novel Treatments for Alzheimers Disease and Related Dementias (R61/R33 Clinical Trial Not Allowed) Apply for RFA AG 23 005 Funding Number: RFA AG 23 005 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
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